Dr Guo Jun Liu is a Senior Research Fellow working with Prof Richard Banati and is using INPHAZE impedance spectroscopy to study the neuronal and glial cells in the central nervous system. The aim is a better understanding of neuronal diseases at the cellular level as well as drug design based on this understanding.
Prof Banati, Dr Liu and INPHAZE have together designed a special sample chamber for cell biology studies, thereby adapting the INPHAZE system for cell biology work.
At the Ian Wark Institute in South Australia, Dr Dusan Losic and his group are developing very interesting systems of nanopore and nanotube materials for applications in molecular separation, biosensing and drug delivery. They are using the INPHAZE spectrometer as one of their central characterization techniques to study molecular transport and the electrical properties of their new materials and devices.
Dr Losic has found that the INPHAZE impedance technique is particularly valuable for the study of biomimetic membranes as well as for the study of membrane-drug and membrane-protein interactions. These are stepping stones towards the world-wide efforts on bio-diagnostic devices for drug screening and drug discovery and biosensing.
Cell membrane work with the INPHAZE tool is also being carried out at ANSTO in the research group of Distinguished Researcher Prof Richard Banati. One of his PhD students has just started her research on hybrid lipid bilayers bound to self-assembled monolayers (SAMs) which themselves are bonded to silicon.
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