ET121  Microchip Platform with C4D Electrodes

ET121 Microchip Platform with C4D Electrodes
ET121 Microchip Platform with C4D Electrodes
  • C4D detector for microfluidic chips
  • C4D electrodes are not required on chip
  • Use with glass or polymer microfluidic chips


The platform can be used as a capacitively-coupled contactless conductivity detector (C4D) for microchip electrophoresis and other experiments. C4D can be used for virtually all charged species: inorganic anions and cations, as well as organic ions, such as carboxylic acids, amines, amino acids, peptides, proteins, DNA fragments, antibiotics and many other pharmaceutical compounds.

An electrophoresis microfluidic chip can be positioned on top of the C4D platform, with the channel positioned so as to pass across the pair of electrodes which transmit and receive the AC signal. The C4D unit generates the excitation waveform, and provides signal filtering and offset.
The platform must be connected to an eDAQ C4D hardware unit.

The base of the microfluidic chip should be less than 200 µm thick, so that the electrodes are as close to the sample channel as possible.

Research Areas

Application Notes


  • Application of capacitively coupled contactless conductivity as an external detector for zone electrophoresis in poly(dimethylsiloxane) chips.   Péter I. Koczka, Ede Bodoki, Attila Gáspár.   Electrophoresis 2015.   DOI:10.1002/elps.201500335
  • ITP of lanthanides in microfluidic PMMA chip.   Y Cong, D Bottenus, B Liu, SB Clark, CF Ivory.   Electrophoresis, 2014.   DOI: 10.1002/elps.201300382
  • Electrophoretic separations in poly (dimethylsiloxane) microchips using mixtures of ionic, nonionic and zwitterionic surfactants.   Q Guan, SD Noblitt, CS Henry.   Electrophoresis, 2012.   DOI: 10.1002/elps.201200255
  • Microchip capillary electrophoresis: Improvements using detection geometry, on-line preconcentration and surface modification.   Q Guan.  PhD Thesis 2012
  • The use of scanning contactless conductivity detection for the characterisation of stationary phases in micro-fluidic chips.  Zarah Walsh, Mercedes Vázquez, Fernando Benito-Lopez, Brett Paull, Mirek Macka, Frantisek Svec, Dermot Diamond.  Lab on a Chip, 2010   DOI: 10.1039/C003584J