BIA-I1117-5mg Ivermectin B1b
Ivermectin B1b is the minor component,<20%, of the commercial anthelmintic, ivermectin.
Binds to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells.
This product is intended for in vitro research and educational experiments. It is not suitable for clinical purposes and is not for human or veterinary use. Made by BioAustralis Sydney, Australia.
- Principles of activation and permeation in an anion-selective Cys-loop receptor. Ryan E. Hibbs, and Eric Gouaux, Nature, 474, 54–60, 2011. DOI:10.1038/nature10139
- Glutamate-gated Chloride Channels. Adrian J. Wolstenholme, Journal of Biological Chemistry, 287, 40232-40238, 2012. DOI: 10.1074/jbc.R112.406280