SDx-R2  tethaPatch

SDx-R2 tethaPatch
SDx-R2 tethaPatch
 

 

The tethaPatch™ is designed for use with a tethaPlate™ for patch-clamp style experiments with a ER466 Potentiostat system on tethered membrane preparations. The six separate chambers of the tethaPlate can be addressed individually for convenient replicate experiments, or separate experiments can be performed in each chamber.

See how to assemble a tethaPlate and make a tethered membrane in the Photos & Videos tab.

Citations

  • The protective effect of osmoprotectant TMAO on bacterial mechanosensitive channels of small conductance MscS/MscK under high hydrostatic pressure. Evgeny Petrov, Paul R. Rohde, Bruce Cornell, and Boris Martinac. Channels, 6:4, 1-10, 2012.DOI: 10.4161/chan.20833

Citations

  • The protective effect of osmoprotectant TMAO on bacterial mechanosensitive channels of small conductance MscS/MscK under high hydrostatic pressure. Evgeny Petrov, Paul R. Rohde, Bruce Cornell, and Boris Martinac. Channels, 6:4, 1-10, 2012.DOI: 10.4161/chan.20833
  • Modelling the Bioelectronic Interface in Engineered Tethered Membranes: From Biosensing to Electroporation.  W. Hoiles, V. Krishnamurthy, and B. Cornell, IEEE Transactions on Biomedical Circuits and Systems, Vol PP Issue 99, 2014.  doi: 10.1109/TBCAS.2014.2357420
  • An Engineered Membrane to Measure Electroporation: Effect of Tethers and Bioelectronic Interface.  W. Hoiles, V. Krishnamurthy, C.G. Cranfield, and B. Cornell,  Biophysical Journal, 107, 1339–1351, 2014.  doi:10.1016/j.bpj.2014.07.056
  • Transient Potential Gradients and Impedance Measures of Tethered Bilayer Lipid Membranes: Pore-Forming Peptide Insertion and the Effect of Electroporation.  C.G. Cranfield, B.A. Cornell, S.L. Grage, P. Duckworth, Sonia Carne, Anne S. Ulrich, Boris Martinac,   Biophysical Journal, 106, 182–189, 2014. doi:10.1016/j.bpj.2013.11.1121

Videos

How to assemble a tethaPlate cartridge
 
Making a tethered membrane
 

View more related videos on the Screencast Training Videos Wiki

 
  • Membrane resistance:10 – 5000 kohm (0.2 - 100 µS)
  • Front panel:   Six way selectror knob.
  • Back panel connetcors: 
             Three 2 mm sockets (for potentiostat electrode leads).
             One 4 mm socket for chassis ground.
  • Sample:   6-chamber tethaPlate
  • Dimensions (h x w x d): 50 x 129 x 168 mm
  • Weight:   ~450 g

 Trademarks: tethaPod, tethaPatch, tethaPlate, and tethaPlasm are trademarks of SDx Tethered Membranes Pty Ltd.